The initial production version was powered by a Mercedes D.II engine inline water-cooled engine, six examples of this variant were built. The basic design was refined and improved. The FF.33e main production reconnaissance variant was powered by a Benz B.III inline engine. This version had longer twin floats, and the under tail central float was eliminated. A radio transmitter replaced its armament, approximately 180 examples of the FF.33e variant were built.
The FF.33 served in both the German and Austria-Hungarian navies. Several other nations purchased the Friedrichshafen FF.33e during the first world war, including Bulgaria, Denmark, Netherlands, and Sweden. The Finnish Air Force purchased two FF.33Es from Germany in February 1918. The first one arrived on April 20, 1918 to Vaasa and the other one in the summer of 1918.